Hi,
I was in Romania in 2004 summer. I crossed the country from west (Arad) to the east (Constanza) and then continued to Bulgaria.
Romania was always safe exept crazy drivers on main roads.
So I would advise you to choose smaller streets although there are many potholes and it can be a bumpy ride.
Especial the carpat mountains and the region around Medias, Brasov and Sibiu is great.
I used the reise know how map from "world mapping project. see
www.reise-know-how.deit is detailed and correct.
People where very friendly and helpful.
for any specific question just ask.
Felix