Hello Constance!
So if anyone of you have done this before, we will be glad to hear of it. Any piece of advice would be useful too !
Together with my wife I cycled the nothern part of the ACA Sierra Cascades Route from Vancouver to Crater Lake back in 2011. In Medford we rented a car and drove back to Seattle along the Pacific coast. Very scenic trip with snowcapped volcanoes and rolling hills.
So, I am ready to answer your questions...
Greetings LUTZ